منابع مشابه
Nefopam in postoperative pain.
Three comparable groups of surgical patients were given nefopam 0.2 mg kg-1 or 0.4 mg kg-1 or morphine 0.15 mg kg-1 for pain relief after operation. Nefopam 0.4 mg kg-1 was equi-analgesic with morphine 0.15 mg kg-1 and produced no obvious cardiovascular or respiratory side-effects.
متن کاملComparison of nefopam and pethidine in postoperative pain.
A double-blind, between-patient, two-dose comparison was comparison was performed with pethidine and nefopam in 100 subjects, the majority of whom were recovering from upper abdominal surgery. Either 15 or 30 mg of nefopam or 50 or 100 mg of pethidine were given by i.m. injection in a random order. All assessments were made by the same observer on the first day after operation, at least 4 h aft...
متن کاملNefopam for the prevention of postoperative pain: quantitative systematic review.
Nefopam, a centrally acting analgesic, has been used in the surgical setting in many countries since the mid-1970s. However, clinical trials provide contflicting results for its analgesic potency. We performed a systematic search (multiple databases, bibliographies, any language, to January 2008) for randomized, placebo-controlled trials of nefopam for the prevention of postoperative pain. Data...
متن کاملThe Effect of Nefopam Infusion during Laparascopic Cholecystectomy on Postoperative Pain
Background: While recovery from remifentanil is fast due to its rapid metabolism, it can induce hyperalgesia by activation of N-methyl-D-aspartic acid (NMDA) receptors. Therefore, administration of NMDA receptor antagonists such as ketamine is effective in relieving hyperalgesia caused by remifentanil. A previous study showed that nefopam administration before anesthesia combined with low-dose ...
متن کاملUse of Nefopam in Perioperative Pain Management; Keeping Nefopam in between
Without mentioning chronic pain, acute postoperative pain has been regarded as a matter of great concern to patients as well as physicians. The 'Pain as the Fifth Vital Sign' initiative may have helped make its control of primary importance in the perioperative management of surgical patients [1]. Extensive literature has demonstrated the benefits of effective postoperative pain control includi...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1979
ISSN: 0007-0912
DOI: 10.1093/bja/51.10.961